I’m really enjoying Fullmetal Alchemist: Brotherhood. I haven’t read the manga, but I loved the first anime, even when it diverged from the source material, so I’m not someone that demands an adaptation be a frame-for-frame duplicate, it just has to be good!
Anime is a totally different medium of entertainment to manga and as such, the dream of a ‘perfect adaptation’ is impossible to realise, because what works in a comic won’t always work for animation. The transition between the two effects everything, from the way the dialogue flows to the selection of a certain scene at the expense of another; an anime series will always have a limited number of episodes to fill and when the source material is particularly long-running, not every single panel can be included. This is a limitation of anime and one should approach an adaptation with that in mind.